Model‐guided design of ligand‐regulated RNAi for programmable control of gene expression
Abstract Progress in constructing biological networks will rely on the development of more advanced components that can be predictably modified to yield optimal system performance. We have engineered an RNA‐based platform, which we call an shRNA switch, that provides for integrated ligand control of...
| Published in: | Molecular Systems Biology |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2008-10-01
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| Online Access: | https://doi.org/10.1038/msb.2008.62 |