Nuclear miR-150 enhances hepatic lipid accumulation by targeting RNA transcripts overlapping the PLIN2 promoter

Summary: Alcohol-associated liver disease is a prevalent chronic liver disease caused by excessive ethanol consumption. This study aims to investigate the role of miR-150 in regulating hepatic lipid homeostasis in alcoholic fatty liver (AFL). miR-150 was mainly distributed in the nucleus of hepatocy...

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Bibliographic Details

Published in:	iScience
Main Authors:	Jiao Luo, Yanan Ji, Ningning Chen, Ge Song, Shuyue Zhou, Xuan Niu, Dianke Yu
Format:	Article
Language:	English
Published:	Elsevier 2023-10-01
Subjects:	Lipid Epigenetics Lipidomics
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004223019144