Mapping the sialic acid-binding sites of LuIII and H-1 parvovirus

ABSTRACT Oncolytic protoparvoviruses, including LuIII, H-1 parvovirus (H-1PV), and the prototypic strain of minute virus of mice (MVMp), can target and destroy cancer cells. Host cell targeting is based largely on the identification and interaction of the virus with the primary receptor. Previously,...

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Bibliographic Details
Published in:Journal of Virology
Main Authors: Kevin Busuttil, Nikéa Pittman, Jon Zachary, Sujata Halder, Lorena Geilen, Amriti Singh, Adam Misseldine, Paulina Kaplonek, Paul Chipman, Jaime Heimburg-Molinaro, Peter H. Seeberger, Mario Mietzsch, Antonette D. Bennett, Robert McKenna
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Subjects:
protoparvovirus
glycan
receptor
oncolytic
Online Access:https://journals.asm.org/doi/10.1128/jvi.00297-25

Internet

https://journals.asm.org/doi/10.1128/jvi.00297-25

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