Identification of anti-citrullinated osteopontin antibodies and increased inflammatory response by enhancement of osteopontin binding to fibroblast-like synoviocytes in rheumatoid arthritis
Abstract Background Anti-citrullinated protein/peptide antibodies (ACPAs) are present in patients at onset and have important pathogenic roles during the course of rheumatoid arthritis (RA). The characteristics of several molecules recognized by ACPA have been studied in RA, but the positivity rate...
| 出版年: | Arthritis Research & Therapy |
|---|---|
| 主要な著者: | Akio Umemoto, Takeshi Kuwada, Koichi Murata, Masahiro Shiokawa, Sakiko Ota, Yoshiki Murotani, Akihiro Itamoto, Kohei Nishitani, Hiroyuki Yoshitomi, Takayuki Fujii, Akira Onishi, Hideo Onizawa, Kosaku Murakami, Masao Tanaka, Hiromu Ito, Hiroshi Seno, Akio Morinobu, Shuichi Matsuda |
| フォーマット: | 論文 |
| 言語: | 英語 |
| 出版事項: |
BMC
2023-02-01
|
| 主題: | |
| オンライン・アクセス: | https://doi.org/10.1186/s13075-023-03007-9 |
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