Synthesis and Antimalarial Evaluation of New 1,3,5-<i>tris</i>[(4-(Substituted-aminomethyl)phenyl)methyl]benzene Derivatives: A Novel Alternative Antiparasitic Scaffold

A series of new 1,3,5-<i>tris</i>[(4-(substituted-aminomethyl)phenyl)methyl]benzene compounds were designed, synthesized, and evaluated <i>in vitro</i> against two parasites (<i>Plasmodium falciparum</i> and <i>Leishmania donovani</i>). The biological...

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Bibliographic Details

Published in:	Drugs and Drug Candidates
Main Authors:	Sandra Albenque-Rubio, Jean Guillon, Anita Cohen, Patrice Agnamey, Solène Savrimoutou, Stéphane Moreau, Jean-Louis Mergny, Luisa Ronga, Ioannis Kanavos, Serge Moukha, Pascale Dozolme, Pascal Sonnet
Format:	Article
Language:	English
Published:	MDPI AG 2023-08-01
Subjects:	antimalarial activity 1,3,5-<i>tris</i>[(4-(substituted-aminomethyl)phenyl)methyl]benzene antileishmanial activity
Online Access:	https://www.mdpi.com/2813-2998/2/3/33