AVID mouse: A versatile platform for real-time, multiscale ATP imaging and spatial systems metabolism analysis in living mice

Summary: We developed the AVID (ATP visualization in vivo directly) mouse, a genetically encoded biosensor mouse enabling real-time, multiscale imaging of ATP dynamics across the whole body, organs, and cellular compartments in living animals. AVID revealed previously undetectable localized ATP depl...

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Bibliographic Details

Published in:	Cell Reports
Main Authors:	Yuichiro Ohnishi, Daiki Setoyama, Hideki Miwa, Norimichi Koitabashi, Riki Ogasawara, Seri Kitada, Naoki Matoba, Takahito Ayano, Kaoru Hiramoto, Ryuto Yasui, Yuki Sugiura, Takahisa Anada, Kosuke Ino, Hinako Matsuda, Takahiro Noma, Shigenori Nonaka, Takashi Izumi, Masahiko Kurabayashi, Makoto Suematsu, Yuya Kunisaki, Motoko Yanagita, Hiromi Imamura, Masamichi Yamamoto
Format:	Article
Language:	English
Published:	Elsevier 2025-09-01
Subjects:	CP: Metabolism
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124725010174