Comparison of antimicrobial activities and resistance mechanisms of eravacycline and tigecycline against clinical Acinetobacter baumannii isolates in China

Tigecycline (TGC) is currently used to treat carbapenem-resistant Acinetobacter baumannii (CRAB) infections, while eravacycline (ERV), a new-generation tetracycline, holds promise as a novel therapeutic option for these infections. However, differences in resistance mechanism between ERV and TGC aga...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Xiandi Chen, Yitan Li, Yingzhuo Lin, Yingyi Guo, Guohua He, Xiaohu Wang, Mingzhen Wang, Jianbo Xu, Mingdong Song, Xixi Tan, Chao Zhuo, Zhiwei Lin
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-09-01
Subjects:	Acinetobacter baumannii eravacycline tigecycline antimicrobial activity resistance mechanism ISAba1 insertion
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2024.1417237/full