Advances in BBB on Chip and Application for Studying Reversible Opening of Blood–Brain Barrier by Sonoporation

The complex structure of the blood–brain barrier (BBB), which blocks nearly all large biomolecules, hinders drug delivery to the brain and drug assessment, thus decelerating drug development. Conventional in vitro models of BBB cannot mimic some crucial features of BBB in vivo including a shear stre...

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Bibliographic Details

Published in:	Micromachines
Main Authors:	Yicong Cai, Kexin Fan, Jiawei Lin, Lin Ma, Fenfang Li
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Subjects:	blood–brain barrier microfluidics ultrasound-mediated drug delivery
Online Access:	https://www.mdpi.com/2072-666X/14/1/112