Safety and Immunogenicity of a 23-Valent Pneumococcal Polysaccharide Vaccine (PPSV23) in Chinese Children, Adults and the Elderly: A Phase 4, Randomized, Double-Blind, Active-Controlled Clinical Trial

Objectives: This randomized, double-blind, active-controlled non-inferiority phase 4 clinical trial was conducted to evaluate the immunogenicity and safety of a 23-valent pneumococcal polysaccharide vaccine (PPSV23) compared to an active comparator vaccine. Methods: Pneumococcal vaccine-naïve partic...

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Bibliographic Details

Published in:	Vaccines
Main Authors:	Xiaoyu Liu, Gang Shi, Yuanyuan Dong, Wanqi Yang, Yinan Wang, Xianying Ye, Juxiang Zhang, Xinyi Yang, Dan Yu, Dan Song, Yuehong Ma, Zeng Wang, Hong Li, Weijun Hu
Format:	Article
Language:	English
Published:	MDPI AG 2025-08-01
Subjects:	23-valent pneumococcal polysaccharide vaccine safety immunogenicity randomized clinical trial
Online Access:	https://www.mdpi.com/2076-393X/13/8/866