Dual Protein-Based Nanocomposite Hydrogel Scaffolds Synergistically Promote Cartilage Regeneration Through Chondrocyte Differentiation and Immunomodulation

The treatment of prolonged inflammation and cartilage damage due to osteoarthritis (OA) is a major clinical challenge. We developed a comprehensive cartilage repair therapy using a dual drug-loaded nanocomposite hydrogel that leveraged the spatiotemporal immunomodulatory effects of a naturally degra...

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Bibliographic Details

Published in:	Engineering
Main Authors:	Huan Lei, Daidi Fan
Format:	Article
Language:	English
Published:	Elsevier 2025-07-01
Subjects:	Nanocomposite hydrogel scaffold Immunomodulation Anti-inflammatory Cartilage regeneration Osteoarthritis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2095809925002875