Insights into the interaction of Fibrinogen with Timolol Maleate and elucidation of binding sites via. spectroscopic and molecular docking study

Abstract Timolol maleate (TM), a beta-blocker drug, is used in treating conditions related to arterial hypertension. Exploring the possible interaction between TM and plasma proteins is crucial for enhancing the drug potency. This interaction study is done to examine the impact of TM on the comportm...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Neha Govind Rao, Anu Radha Pathania, Harman Deep Kour, Suhas Ballal, Abhayveer Singh, Abhijit Bhowmik, Balewgize Amare Zeru
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Subjects:
Circular dichroism
Fibrinogen
Fluorescence spectroscopy
Molecular Docking
Timolol maleate
Online Access:https://doi.org/10.1038/s41598-025-00929-z

Internet

https://doi.org/10.1038/s41598-025-00929-z

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