Responsive manganese-based nanoplatform amplifying cGAS-STING activation for immunotherapy

Abstract Background The activation of the cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes (cGAS-STING) signaling pathway has attracted great attention for its ability to up-regulate innate immune response and thus enhance cancer immunotherapy. However,...

Full description

Bibliographic Details

Published in:	Biomaterials Research
Main Authors:	Qingbin He, Runxiao Zheng, Junchi Ma, Luyang Zhao, Yafang Shi, Jianfeng Qiu
Format:	Article
Language:	English
Published:	American Association for the Advancement of Science (AAAS) 2023-04-01
Subjects:	Tumor responsiveness cGAS-STING signaling pathway Immunotherapy Manganese ions Reactive oxygen species
Online Access:	https://doi.org/10.1186/s40824-023-00374-x