Targeting ferroptosis in cancer stem cells: A novel strategy to improve cancer treatment

Ferroptosis, a distinct regulated cell death process characterized by iron retention and lipid peroxidation, plays a crucial role in the survival of cancer stem cells (CSCs), key contributors to cancer initiation, progression, and recurrence. CSCs exhibit enhanced iron uptake and altered lipid metab...

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Bibliographic Details

Published in:	Genes and Diseases
Main Authors:	Luyao Wang, Ye Zhu, Chengying Huang, Qiuming Pan, Junxi Wang, Hongrui Li, Yudi Huang, Guozhong Yi, Zhiyong Li, Songtao Qi, Guanglong Huang, Shanqiang Qu
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2025-11-01
Subjects:	Cancer stemcells (CSCs) Cell signaling Drug target Ferroptosis Iron metabolism
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352304225001679