Activation of Gingival Fibroblasts by Bacterial Cyclic Dinucleotides and Lipopolysaccharide

Human gingival fibroblasts (HGFs) recognize microbe-associated molecular patterns (MAMPs) and respond with inflammatory proteins. Simultaneous impacts of bacterial cyclic di-guanosine monophosphate (c-di-GMP), cyclic di-adenosine monophosphate (c-di-AMP), and lipopolysaccharide (LPS) on gingival ker...

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Bibliographic Details

Published in:	Pathogens
Main Authors:	Samira Elmanfi, Herman O. Sintim, Jie Zhou, Mervi Gürsoy, Eija Könönen, Ulvi K. Gürsoy
Format:	Article
Language:	English
Published:	MDPI AG 2020-09-01
Subjects:	lipopolysaccharide inflammation interleukin matrix metalloproteinases human gingival fibroblasts
Online Access:	https://www.mdpi.com/2076-0817/9/10/792