Axonal mitophagy in retinal ganglion cells

Abstract Neurons, exhibiting unique polarized structures, rely primarily on the mitochondrial production of ATP to maintain their hypermetabolic energy requirements. To maintain a normal energy supply, mitochondria are transported to the distal end of the axon. When mitochondria within the axon are...

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Bibliographic Details
Published in:Cell Communication and Signaling
Main Authors: Yang Liang, Yulin Li, Qing Jiao, Muyang Wei, Yan Wang, Aoteng Cui, Zhihui Li, Guangyu Li
Format: Article
Language:English
Published: BMC 2024-07-01
Subjects:
Online Access:https://doi.org/10.1186/s12964-024-01761-0