LC-HRMS-Based Identification of Transformation Products of the Drug Salinomycin Generated by Electrochemistry and Liver Microsome

The drug salinomycin (SAL) is a polyether antibiotic and used in veterinary medicine as coccidiostat and growth promoter. Recently, SAL was suggested as a potential anticancer drug. However, transformation products (TPs) resulting from metabolic and environmental degradation of SAL are incompletely...

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Bibliographic Details

Published in:	Antibiotics
Main Authors:	Lisa Knoche, Jan Lisec, Tanja Schwerdtle, Matthias Koch
Format:	Article
Language:	English
Published:	MDPI AG 2022-01-01
Subjects:	salinomycin ionophore antibiotics transformation product electrochemistry rat/human liver microsomes HRMS
Online Access:	https://www.mdpi.com/2079-6382/11/2/155