A functional mechanism for a non-coding variant near AGTR2 associated with risk for preterm birth

Abstract Background Preterm birth (PTB), defined as delivery before 37 gestational weeks, imposes significant public health burdens. A recent maternal genome-wide association study of spontaneous PTB identified a noncoding locus near the angiotensin II receptor type 2 (AGTR2) gene. Genotype-Tissue E...

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Bibliographic Details
Published in:BMC Medicine
Main Authors: Li Wang, Robert M. Rossi, Xiaoting Chen, Jing Chen, Jilian Runyon, Mehak Chawla, Daniel Miller, Carmy Forney, Arthur Lynch, Xuzhe Zhang, Fansheng Kong, Bo Jacobsson, Leah C. Kottyan, Matthew T. Weirauch, Ge Zhang, Louis J. Muglia
Format: Article
Language:English
Published: BMC 2023-07-01
Subjects:
Functional studies
Preterm birth
Non-coding variant
AGTR2
Online Access:https://doi.org/10.1186/s12916-023-02973-w

Internet

https://doi.org/10.1186/s12916-023-02973-w

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