Mechanistic engineering of celastrol liposomes induces ferroptosis and apoptosis by directly targeting VDAC2 in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of most common and deadliest malignancies. Celastrol (Cel), a natural product derived from the Tripterygium wilfordii plant, has been extensively researched for its potential effectiveness in fighting cancer. However, its clinical application has been hindered b...

書誌詳細
出版年:	Asian Journal of Pharmaceutical Sciences
主要な著者:	Piao Luo, Qian Zhang, Shuo Shen, Yehai An, Lixia Yuan, Yin-Kwan Wong, Sizhe Huang, Shaohui Huang, Jingnan Huang, Guangqing Cheng, Jiahang Tian, Yu Chen, Xiaoyong Zhang, Weiguang Li, Songqi He, Jigang Wang, Qingfeng Du
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2023-11-01
主題:	Celastrol VDAC2 Ferroptosis Apoptosis Hepatocellular carcinoma Liposomes
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S1818087623001009

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