Novel pH-Responsive Cubosome and Hexosome Lipid Nanocarriers of SN-38 Are Prospective for Cancer Therapy

pH-responsive nanoparticles enable the selective delivery of a chemotherapeutic agent to tumours while reducing adverse effects. Herein we synthesised four novel aminolipids and developed pH-responsive nanostructured lipid nanoparticles (LNP), which exhibited a slow-releasing hexagonal structure (H&...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Sarigama Rajesh, Jiali Zhai, Calum J. Drummond, Nhiem Tran
Format:	Article
Language:	English
Published:	MDPI AG 2022-10-01
Subjects:	pH-responsive cubosomes hexosomes lipid-nanoparticles (LNPs) SN-38 ionisable lipids
Online Access:	https://www.mdpi.com/1999-4923/14/10/2175