Concentration-Dependent Inhibitory Effect of Irbesartan on Renal Uric Acid Transporters

Hyperuricemia is currently recognized as a risk factor for cardiovascular diseases. It has been reported that the angiotensin II–receptor blocker (ARB) losartan decreases serum uric acid level. In this study, the effects of another ARB, irbesartan, on [14C]uric acid–transport activity of renal uric...

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Bibliographic Details
Published in:Journal of Pharmacological Sciences
Main Authors: Makiko Nakamura, Naohiko Anzai, Promsuk Jutabha, Hiroyuki Sato, Hiroyuki Sakurai, Kimiyoshi Ichida
Format: Article
Language:English
Published: Elsevier 2010-01-01
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319308886