Chemical stabilization of the extracellular matrix attenuates growth of experimentally induced abdominal aorta aneurysms in a large animal model

Objective: The goal of the present study was to test the safety and efficacy of chemical stabilization of the arterial extracellular matrix as a novel nonoperative treatment of abdominal aortic aneurysms (AAAs) in a clinically relevant large animal model. Methods: To achieve matrix stabilization, we...

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Bibliographic Details

Published in:	JVS - Vascular Science
Main Authors:	Dan Simionescu, PhD, Megan Casco, PhD, Jake Turner, BS, Nicholas Rierson, BS, Jianing Yue, MD, PhD, Kelvin Ning, MS
Format:	Article
Language:	English
Published:	Elsevier 2020-01-01
Subjects:	AAA animal model Nonoperative management of AAA Pentagalloylglucose Polyphenols
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666350320300067