Inhibiting glycolysis facilitated checkpoint blockade therapy for triple-negative breast cancer
Abstract Cancer cells are characterized by their altered energy metabolism. A hallmark of cancer metabolism is aerobic glycolysis, also called the Warburg effect. Hexokinase 2 (HK2), a crucial glycolytic enzyme converting glucose to glucose-6-phosphate, has been identified as a central player in the...
| الحاوية / القاعدة: | Discover Oncology |
|---|---|
| المؤلفون الرئيسيون: | , , , , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
Springer
2025-04-01
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1007/s12672-025-02320-w |