Enhancing constituent estimation in nucleic acid mixture models using spectral annealing inference and MS/MS information

Mass spectrometry (MS) is a powerful analytical technique employed for a variety of applications including drug development, quality assurance, food inspection, and monitoring environmental pollutants. Recently, in the production of actively developed antibody and nucleic acid pharmaceuticals, impur...

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Bibliographic Details

Published in:	Frontiers in Analytical Science
Main Authors:	Taichi Tomono, Satoshi Hara, Junko Iida, Takashi Washio
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-02-01
Subjects:	LC-MS ESI chemometrics Bayesian inference deconvolution signal processing
Online Access:	https://www.frontiersin.org/articles/10.3389/frans.2025.1494615/full