Mutations of SARS-CoV-2 RBD May Alter Its Molecular Structure to Improve Its Infection Efficiency

The receptor-binding domain (RBD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mediates the viral–host interaction and is a target for most neutralizing antibodies. Nevertheless, SARS-CoV-2 RBD mutations pose a threat due to their role in host cell entry via the human angiotensin-...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Ahmed L. Alaofi, Mudassar Shahid
Format:	Article
Language:	English
Published:	MDPI AG 2021-08-01
Subjects:	wild-type RBD mutant RBDs SARS-CoV-2 molecular dynamics simulations RBD flexibility principle component analysis
Online Access:	https://www.mdpi.com/2218-273X/11/9/1273