Tumor-associated macrophages (TAMs): Constructing an immunosuppressive microenvironment bridge for pancreatic ductal adenocarcinoma (PDAC)

Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease with increasing incidences worldwide. The overall 5-year survival rate remains low, underscoring the urgent need for effective therapies. Despite the promising efficacy of immunotherapy for various solid tumors, its benefits for pancreatic c...

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Bibliographic Details

Published in:	Cancer Pathogenesis and Therapy
Main Authors:	Runjie Liu, Jianang Li, Liang Liu, Wenquan Wang, Jinbin Jia
Format:	Article
Language:	English
Published:	Elsevier 2025-05-01
Subjects:	Pancreatic cancer Macrophages Tumor microenvironment Immunosuppression
Online Access:	http://www.sciencedirect.com/science/article/pii/S2949713224000557