Positive and Negative Regulation of Th17 Cell Differentiation: Evaluating The Impact of RORC2

Objective: Th17 cells are known to be involved in some types of inflammations and autoimmune disorders. RORC2 is the key transcription factor coordinating Th17 cell differentiation. Thus, blocking RORC2 may be useful in suppressing Th17-dependent inflammatory processes. The aim was to silence ROR...

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Bibliographic Details

Published in:	Cell Journal
Main Authors:	Mazdak Ganjalikhani Hakemi, Kamran Ghaedi, Vida Homayouni, Alireza Andalib, Mohsen Hosseini, Abbas Rezaei
Format:	Article
Language:	English
Published:	Royan Institute (ACECR), Tehran 2014-04-01
Subjects:	IL-17 IL-23R RORC2 siRNA Th17
Online Access:	http://celljournal.org/library/upload/article/af_552533763363256624423434664723442246625613-Mazdak%20Ganjalikhani%20Hakemi-phone.pdf