Type IV secretion of Helicobacter pylori CagA into oral epithelial cells is prevented by the absence of CEACAM receptor expression

Abstract Background Helicobacter pylori typically colonizes the human stomach, but it can occasionally be detected in the oral cavity of infected persons. Clinical outcome as a result of gastric colonization depends on presence of the pathogenicity island cagPAI that encodes a type-IV secretion syst...

Full description

Bibliographic Details

Published in:	Gut Pathogens
Main Authors:	Nicole Tegtmeyer, Tabita Denisia Ghete, Verena Schmitt, Torsten Remmerbach, Maria Celeste C. Cortes, Edgardo M. Bondoc, Hans-Ludwig Graf, Bernhard B. Singer, Christian Hirsch, Steffen Backert
Format:	Article
Language:	English
Published:	BMC 2020-05-01
Subjects:	AGS HN CAL-27 BHY CEACAM CagA
Online Access:	http://link.springer.com/article/10.1186/s13099-020-00363-8