3-Hydroxyanthranilic Acid Delays Paralysis in <i>Caenorhabditis elegans</i> Models of Amyloid-Beta and Polyglutamine Proteotoxicity

Age is the primary risk factor for neurodegenerative diseases such as Alzheimer’s and Huntington’s disease. Alzheimer’s disease is the most common form of dementia and a leading cause of death in the elderly population of the United States. No effective treatments for these diseases currently exist....

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Bradford T. Hull, Kayla M. Miller, Caroline Corban, Grant Backer, Susan Sheehan, Ron Korstanje, George L. Sutphin
Format:	Article
Language:	English
Published:	MDPI AG 2024-05-01
Subjects:	metabolism tryptophan kynurenine Alzheimer’s disease Huntington’s disease neurodegeneration
Online Access:	https://www.mdpi.com/2218-273X/14/5/599