RIPK1-RIPK3-MLKL-dependent necrosis promotes the aging of mouse male reproductive system
A pair of kinases, RIPK1 and RIPK3, as well as the RIPK3 substrate MLKL cause a form of programmed necrotic cell death in mammals termed necroptosis. We report here that male reproductive organs of both Ripk3- and Mlkl-knockout mice retain ‘youthful’ morphology and function into advanced age, while...
| الحاوية / القاعدة: | eLife |
|---|---|
| المؤلفون الرئيسيون: | , , , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
eLife Sciences Publications Ltd
2017-08-01
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://elifesciences.org/articles/27692 |