Berberine prevents lethal EV71 neurological infection in newborn mice

Enterovirus 71 (EV71) is the major pathogen causing fatal neurological complications of hand, foot, and mouth disease (HFMD) in young children. Currently no effective antiviral therapy is available. In the present study, we found that natural compound Berberine (BBR) displayed potent inhibitory effe...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Guangyi Cui, Han Wang, Chongting Yang, Xiaoxiao Zhou, Junyi Wang, Tong Wang, Tonghui Ma
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-10-01
Subjects:	hand foot and mouth disease EV71 BBR neural infection astrocytes inflammatory storms
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.1027566/full