Mutant and curli-producing E. coli enhance the disease phenotype in a hSOD1-G93A mouse model of ALS

Abstract The gut microbiome is a potential non-genetic contributing factor for Amyotrophic Lateral Sclerosis. Differences in gut microbial communities have been detected between ALS subjects and healthy controls, including an increase in Escherichia coli in ALS subjects. E. coli and other gram-negat...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Zimple Kurlawala, Joseph D. McMillan, Richa A. Singhal, Johnny Morehouse, Darlene A. Burke, Sophia M. Sears, Eleonora Duregon, Levi J. Beverly, Leah J. Siskind, Robert P. Friedland
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-04-01
Online Access:	https://doi.org/10.1038/s41598-023-32594-5