Safety outcome trials in four mainline medical journals 30 years apart: a narrative review and the need for the transparency of informed consents

Abstract Background It was our impression that safety outcome trials were getting more frequent, raising ethical issues mainly related to patient autonomy. We and others had also proposed this autonomy would be best served if wording of the informed consents would be in the public domain. Methods In...

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Bibliographic Details

Published in:	Trials
Main Authors:	Sinem Nihal Esatoglu, Ayse Ozdede, Yesim Ozguler, Koray Tascilar, Hasan Yazici
Format:	Article
Language:	English
Published:	BMC 2025-01-01
Subjects:	Randomized controlled trials Informed consent Study aim Primary outcome measures Nuremberg Code Helsinki Code
Online Access:	https://doi.org/10.1186/s13063-025-08732-x