LINC00618 facilitates growth and metastasis of hepatocellular carcinoma via elevating cholesterol synthesis by promoting NSUN2-mediated SREBP2 m5C modification

Dysregulation of cholesterol metabolism is an important feature of cancer development. There are limited reports on the involvement of lncRNAs in hepatocellular carcinoma (HCC) progression via the cholesterol metabolism pathway. The present study explored the effect of LINC00618 on HCC growth and me...

Full description

Bibliographic Details

Published in:	Ecotoxicology and Environmental Safety
Main Authors:	Rong Li, Shunle Li, Lin Shen, Junhui Li, Di Zhang, Jinmin Yu, Lanxuan Huang, Na Liu, Hongwei Lu, Meng Xu
Format:	Article
Language:	English
Published:	Elsevier 2024-10-01
Subjects:	Hepatocellular carcinoma LINC00618 NSUN2 SREBP2 Cholesterol synthesis EMT
Online Access:	http://www.sciencedirect.com/science/article/pii/S0147651324011400