Norswertianolin Promotes Cystathionine γ-Lyase Activity and Attenuates Renal Ischemia/Reperfusion Injury and Hypertension

Cystathionine gamma-lyase (CSE)/hydrogen sulfide (H2S) plays a protective role in cardiovascular diseases including hypertension and ischemia/reperfusion (I/R) injury. This study was aimed to screen natural small molecule compounds that activate CSE activity and then evaluate its effect(s) on kidney...

Full description

Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Yaping Niu, Congkuo Du, Changting Cui, Haizeng Zhang, Yue Deng, Jun Cai, Zhenzhen Chen, Bin Geng
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-07-01
Subjects:	cystathionine gamma-lyase hydrogen sulfide norswertianolin renal ischemia/reperfusion hypertension
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2021.677212/full