Genetic variation in genes regulating skeletal muscle regeneration and tissue remodelling associated with weight loss in chronic obstructive pulmonary disease

Abstract Background Chronic obstructive pulmonary disease (COPD) is the third leading cause of death globally. COPD patients with cachexia or weight loss have increased risk of death independent of body mass index (BMI) and lung function. We tested the hypothesis genetic variation is associated with...

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Bibliographic Details

Published in:	Journal of Cachexia, Sarcopenia and Muscle
Main Authors:	Preeti Lakshman Kumar, Ava C. Wilson, Alison Rocco, Michael H. Cho, Emily Wan, Brian D. Hobbs, George R. Washko, Victor E. Ortega, Stephanie A. Christenson, Xingnan Li, J. Michael Wells, Surya P. Bhatt, Dawn L. DeMeo, Sharon M. Lutz, Harry Rossiter, Richard Casaburi, Stephen I. Rennard, David A. Lomas, Wassim W. Labaki, Ruth Tal‐Singer, Russel P. Bowler, Craig P. Hersh, Hemant K. Tiwari, Mark Dransfield, Anna Thalacker‐Mercer, Deborah A. Meyers, Edwin K. Silverman, Merry‐Lynn N. McDonald, COPDGene, ECLIPSE and SPIROMICS investigators
Format:	Article
Language:	English
Published:	Wiley 2021-12-01
Subjects:	GWAS Cachexia Weight loss COPD Genetics Biomarkers
Online Access:	https://doi.org/10.1002/jcsm.12782