TORC: Target-Oriented Reference Construction for supervised cell-type identification in scRNA-seq

Abstract Cell-type identification is a crucial step in single cell RNA-seq (scRNA-seq) data analysis, for which supervised methods are preferred due to their accuracy and efficiency. Performance is highly dependent on the quality of the reference data, but there is no method for selecting and constr...

Full description

Bibliographic Details

Published in:	Genome Biology
Main Authors:	Xin Wei, Wenjing Ma, Zhijin Wu, Hao Wu
Format:	Article
Language:	English
Published:	BMC 2025-06-01
Subjects:	ScRNA-seq Supervised learning Cell-type identification Reference construction
Online Access:	https://doi.org/10.1186/s13059-025-03614-6