Leveraging diverse liquid–liquid phase separation patterns to predict the prognosis and immunotherapy of pediatric acute myeloid leukemia

Abstract Background Despite improvements in 5-year survival rates for pediatric acute myeloid leukemia (P-AML) over recent decades, the relapse rate remains high. This challenge is compounded by the absence of reliable prognostic biomarkers, which limits the effectiveness of predictive, preventive,...

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Bibliographic Details

Published in:	BMC Cancer
Main Authors:	Min Kong, Yezhen Yang, Zhixiang Wu, Ying Li, Zhijuan Kang, Qin Zhao, Huan Chang, Zuocheng Yang
Format:	Article
Language:	English
Published:	BMC 2025-08-01
Subjects:	Pediatric acute myeloid leukemia Liquid-liquid phase separation Prognosis Immunotherapy efficacy Immune infiltration
Online Access:	https://doi.org/10.1186/s12885-025-14718-4