Novel 2-Thiouracil-5-Sulfonamide Derivatives: Design, Synthesis, Molecular Docking, and Biological Evaluation as Antioxidants with 15-LOX Inhibition

New antioxidant agents are urgently required to combat oxidative stress, which is linked to the emergence of serious diseases. In an effort to discover potent antioxidant agents, a novel series of 2-thiouracil-5-sulfonamides (<b>4</b>–<b>9</b>) were designed and synthesized....

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Bibliographic Details

Published in:	Molecules
Main Authors:	Naglaa M. Ahmed, Ahmed H. Lotfallah, Mohamed S. Gaballah, Samir M. Awad, Moustafa K. Soltan
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Subjects:	sulfonamides antioxidant DPPH 15-LOX molecular docking
Online Access:	https://www.mdpi.com/1420-3049/28/4/1925