Enhanced therapeutic window for antimicrobial Pept-ins by investigating their structure-activity relationship.

The overconsumption and inappropriate use of antibiotics is escalating antibiotic resistance development, which is now one of the 10 top threats to global health. Introducing antibiotics with a novel mode of action into clinical use is urgently needed to address this issue. Deliberately inducing agg...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Guiqin Wu, Laleh Khodaparast, Ladan Khodaparast, Matthias De Vleeschouwer, Nikolaos Louros, Rodrigo Gallardo, Pengpeng Yi, Frederic Rousseau, Joost Schymkowitz
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2023-01-01
Online Access:	https://doi.org/10.1371/journal.pone.0283674