Eosinophilic esophagitis-associated epithelial remodeling may limit esophageal carcinogenesis

IntroductionUnder homeostatic conditions, esophageal epithelium displays a proliferation/differentiation gradient that is generated as proliferative basal cells give rise to suprabasal cells then terminally differentiated superficial cells. This proliferation/differentiation gradient is often pertur...

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Bibliographic Details

Published in:	Frontiers in Allergy
Main Authors:	Annie D. Fuller, Adam L. Karami, Mohammad Faujul Kabir, Alena Klochkova, Jazmyne L. Jackson, Anbin Mu, Yinfei Tan, Andres J. Klein-Szanto, Kelly A. Whelan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Subjects:	eosinophilic esophagitis esophageal squamous cell carcinoma esophageal epithelium atopy cell fate trajectory cell differentiation
Online Access:	https://www.frontiersin.org/articles/10.3389/falgy.2023.1086032/full