Amyloid pathology arrangements in Alzheimer’s disease brains modulate in vivo seeding capability

Abstract Amyloid-β (Aβ) misfolding is one of the hallmark pathological features of Alzheimer’s disease (AD). AD can manifest with diverse symptomatology including variable rates of cognitive decline, duration of clinical disease, and other detrimental changes. Several reports suggest that conformati...

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Bibliographic Details

Published in:	Acta Neuropathologica Communications
Main Authors:	Claudia Duran-Aniotz, Ines Moreno-Gonzalez, Nazaret Gamez, Nelson Perez-Urrutia, Laura Vegas-Gomez, Claudio Soto, Rodrigo Morales
Format:	Article
Language:	English
Published:	BMC 2021-03-01
Subjects:	Alzheimer’s disease Amyloid-beta Prions Strains Pathology
Online Access:	https://doi.org/10.1186/s40478-021-01155-0