Humanization, Radiolabeling and Biodistribution Studies of an IgG₁-Type Antibody Targeting Uncomplexed PSA for Theranostic Applications

Metastatic castration-resistant prostate cancer is today incurable. Conventional imaging methods have limited detection, affecting their ability to give an accurate outcome prognosis, and current therapies for metastatic prostate cancer are insufficient. This inevitably leads to patients relapsing w...

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Bibliographic Details

Published in:	Pharmaceuticals
Main Authors:	Joanna Strand, Kjell Sjöström, Urpo J. Lamminmaki, Oskar Vilhelmsson Timmermand, Sven-Erik Strand, Thuy A. Tran
Format:	Article
Language:	English
Published:	MDPI AG 2021-12-01
Subjects:	prostate cancer imaging humanization 5A10 fPSA theranostics
Online Access:	https://www.mdpi.com/1424-8247/14/12/1251