Foot-and-mouth disease virus-derived dendrimer peptides induce germinal center-dependent antibody responses and IgG1 plasma cell differentiation in mice

Abstract Our previous findings demonstrated that the B2T dendrimer peptide, harboring B- and T-cell foot-and-mouth disease virus (FMDV) epitopes, confers protection in swine and elicits in mice significant levels of neutralizing antibodies, a key correlate of protection against FMDV. Here, we use a...

Full description

Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Marta Iborra-Pernichi, Patricia de León, Elisa Torres, Sira Defaus, Esther Blanco, David Andreu, Nuria Martínez-Martín, Francisco Sobrino
Format:	Article
Language:	English
Published:	Nature Portfolio 2026-03-01
Subjects:	FMD FMDV B cell response T dependent Germinal center Peptide-vaccines
Online Access:	https://doi.org/10.1038/s41598-026-42982-2