Longitudinal long term follow up investigation on the carcinogenic impact of polyhexamethylene guanidine phosphate in rat models

Abstract Polyhexamethylene guanidine phosphate (PHMG-p) is a major component in humidifier disinfectants, which cause life-threatening lung injuries. However, to our knowledge, no published studies have investigated associations between PHMG-p dose and lung damage severity with long-term follow-up....

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Sang Hoon Jeong, Hong Lee, Yoon Jeong Nam, Ja Young Kang, Hyejin Lee, Jin Young Choi, Yu-Seon Lee, Jaeyoung Kim, Yoon Hee Park, Su A. Park, Hangseok Choi, Eun-Kee Park, Yong-Wook Baek, Jungyun Lim, Suejin Kim, Cherry Kim, Ju-Han Lee
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-03-01
Subjects:	Rat model Polyhexamethylene guanidine phosphate Chest CT Lung cancer Lung fibrosis
Online Access:	https://doi.org/10.1038/s41598-024-57605-x