Role of Ezrin Phosphorylation in HIV-1 Replication

Host-cell expression of the ezrin protein is required for CXCR4 (X4)-tropic HIV-1 infection. Ezrin function is regulated by phosphorylation at threonine-567. This study investigates the role of ezrin phosphorylation in HIV-1 infection and virion release. We analyzed the effects of ezrin mutations in...

Full description

Bibliographic Details
Published in:Frontiers in Microbiology
Main Authors: Haruka Kamiyama, Mai Izumida, Yuria Umemura, Hideki Hayashi, Toshifumi Matsuyama, Yoshinao Kubo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Subjects:
HIV-1
ezrin
viral entry
viral assembly
viral budding
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01912/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01912/full

Similar Items