An ovine septic shock model of live bacterial infusion

Abstract Background Escherichia coli is the most common cause of human bloodstream infections and bacterial sepsis/septic shock. However, translation of preclinical septic shock resuscitative therapies remains limited mainly due to low-fidelity of available models in mimicking clinical illness. To o...

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Bibliographic Details
Published in:Intensive Care Medicine Experimental
Main Authors: Nchafatso G. Obonyo, Sainath Raman, Jacky Y. Suen, Kate M. Peters, Minh-Duy Phan, Margaret R. Passmore, Mahe Bouquet, Emily S. Wilson, Kieran Hyslop, Chiara Palmieri, Nicole White, Kei Sato, Samia M. Farah, Lucia Gandini, Keibun Liu, Gabriele Fior, Silver Heinsar, Shinichi Ijuin, Sun Kyun Ro, Gabriella Abbate, Carmen Ainola, Noriko Sato, Brooke Lundon, Sofia Portatadino, Reema H. Rachakonda, Bailey Schneider, Amanda Harley, Louise E. See Hoe, Mark A. Schembri, Gianluigi Li Bassi, John F. Fraser
Format: Article
Language:English
Published: SpringerOpen 2024-10-01
Subjects:
Haemodynamic monitoring
Resuscitation
Escherichia coli
ST131
Animal model
Preclinical
Online Access:https://doi.org/10.1186/s40635-024-00684-x

Internet

https://doi.org/10.1186/s40635-024-00684-x

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