Disseminated intravascular coagulation phenotype is regulated by the TRPM7 channel during sepsis

Abstract Background Sepsis is an uncontrolled inflammatory response against a systemic infection that results in elevated mortality, mainly induced by bacterial products known as endotoxins, producing endotoxemia. Disseminated intravascular coagulation (DIC) is frequently observed in septic patients...

Full description

Bibliographic Details

Published in:	Biological Research
Main Authors:	Ivanka Jiménez-Dinamarca, Yolanda Prado, Pablo Tapia, Sebastian Gatica, Clemens Alt, Charles P. Lin, Cristian Reyes-Martínez, Carmen G. Feijóo, Cristobal Aravena, Alejandra González-Canacer, Simón Correa, Diego Varela, Claudio Cabello-Verrugio, Felipe Simon
Format:	Article
Language:	English
Published:	BMC 2023-03-01
Subjects:	TRPM7 Coagulation Sepsis Endothelium Organ dysfunction
Online Access:	https://doi.org/10.1186/s40659-023-00419-4