A stress response p38 MAP kinase inhibitor SB202190 promoted TFEB/TFE3-dependent autophagy and lysosomal biogenesis independent of p38

TFEB (transcription factor EB) and TFE3 (transcription factor E3) are “master regulators” of autophagy and lysosomal biogenesis. The stress response p38 mitogen-activated protein (MAP) kinases affect multiple intracellular responses including inflammation, cell growth, differentiation, cell death, s...

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Bibliographic Details

Published in:	Redox Biology
Main Authors:	Chuanbin Yang, Zhou Zhu, Benjamin Chun-Kit Tong, Ashok Iyaswamy, Wen-Jian Xie, Yu Zhu, Sravan Gopalkrishnashetty Sreenivasmurthy, Krishnamoorthi Senthilkumar, King-Ho Cheung, Ju-Xian Song, Hong-Jie Zhang, Min Li
Format:	Article
Language:	English
Published:	Elsevier 2020-05-01
Subjects:	p38 inhibitor SB202190 SB203580 TFEB TFE3 Autophagy and lysosomal biogenesis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213231719311802