Glutathione peroxidase 4 overexpression induces anomalous subdiffusion and impairs glioblastoma cell growth

Abstract Glioblastoma tumors are the most common and aggressive adult central nervous system malignancy. Nearly all patients experience disease progression, which significantly contributes to disease mortality. Recently, it has been suggested that recurrent tumors may be characterized by a ferroptos...

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Bibliographic Details

Published in:	Journal of Biological Engineering
Main Authors:	Nahom Teferi, Akalanka Ekanayake, Stephenson B. Owusu, Thomas O. Moninger, Jann N. Sarkaria, Alexei V. Tivanski, Michael S. Petronek
Format:	Article
Language:	English
Published:	BMC 2024-12-01
Subjects:	Ferroptosis Glioblastoma Cell stiffness Cell motility Tumor progression Glutathione peroxidase 4
Online Access:	https://doi.org/10.1186/s13036-024-00472-x