Quantification of polysorbate 80 in biopharmaceutical formulations implementing an optimized colorimetric approach

Objectives. We hereby describe an improvement of a previously developed quantification technique for polysorbate 80 in biopharmaceutical formulations (darbepoetin alfa and eculizumab) and report the validation of the new approach.Methods. Polysorbate was isolated from analyte samples by protein prec...

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Bibliographic Details

Published in:	Тонкие химические технологии
Main Authors:	A. S. Seregin, N. V. Orlova, A. D. Askretkov, D. I. Zybin, Yu. A. Seregin
Format:	Article
Language:	Russian
Published:	MIREA - Russian Technological University 2020-07-01
Subjects:	validation darbepoetin alfa eculizumab polysorbate precipitation ferric thiocyanate
Online Access:	https://www.finechem-mirea.ru/jour/article/view/1625